Figure 1.

Taste receptors TIR2 and T1R3 in tongue (A), small intestine (B) and colon (C); glucose transporters (D) and incretins (E) in small intestine. Serum levels of glucose insulinotropic peptide (GIP) (F) and glucagon like peptide (GLP-1) (G) of rats fed with different sweeteners with or without high fat diet. The data are expressed as the mean ± SEM (n = 6). Results were considered statistically significant at p < 0.05. Significant differences among groups are indicated by letters, where a > b > c > d > e > f > g.