Figure 5.

Effect of type of sweeteners on histological morphology and expression of adiponectin and UCP-1 in brown adipose tissue. Hematoxylin-Eosin staining (HE) of BAT of rats fed different sweetener with control (A) or high fat diet (C). Brown adipocyte size (B,D); Relative expression of adiponectin (E) and uncoupling protein 1 (UCP-1) (F). The data are expressed as the mean ± SEM (n = 6). Results were considered statistically significant at p < 0.05. Significant differences among groups groups are indicated by letters, where a > b > c > d > e > f.