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. 2019 Mar 30;11(4):455. doi: 10.3390/cancers11040455

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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CXCR7 expression in different NSCLC cell lines with or without gefitinib treatment and CXCR7 expression in NSCLC patients. (a) Western blot analysis of H1299, H1650 EGFR^wt/wt, and EGFR^−/− cells. (b) Western blot analysis of H1299, H1650, and HCC827 cells treated with different doses of gefitinib over time. (c) Immunohistochemical staining of CXCR7 in NSCLC primary tumor samples (n = 47). The blue and black arrows show the expression of CXCR7 in mature and less differentiated squamous cell lung carcinoma (SQCC), respectively.