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. 2019 Apr 7;11(4):495. doi: 10.3390/cancers11040495

Table 4.

Correlation of PpIX concentration and relative mRNA levels in carcinomas and sarcomas.

PpIX vs. PEPT1 PEPT2 GAT2 TAUT PAT1 ABCG2 ABCB6
Carcinomas r −0.1493 0.2446 −0.03814 −0.1145 −0.5074 0.08762 −0.02171
R square 0.02230 0.05985 0.001454 0.01312 0.2575 0.007678 0.0004713
P values 0.3507 0.2629 0.4612 0.3846 0.0816 0.4113 0.4779
Sarcomas r −0.4824 0.1172 −0.7321 0.09674 −0.6289 −0.2354 −0.2986
R square 0.2327 0.01374 0.5360 0.009359 0.3955 0.05540 0.08914
P values 0.1663 0.4125 0.0490 0.4277 0.0905 0.3267 0.2827
PpIX vs. HMBS UROS UROD CPOX FECH HO-1
Carcinomas r −0.2590 −0.4702 −0.4961 −0.3044 −0.6368 −0.4461
R square 0.06709 0.2211 0.2461 0.09268 0.4055 0.1990
P values 0.2505 0.1007 0.0872 0.2129 0.0326 0.1144
Sarcomas r 0.2535 0.7561 0.04538 0.3548 −0.001319 0.4609
R square 0.06428 0.5717 0.002059 0.1259 1.739e-006 0.2124
P values 0.3139 0.0410 0.4660 0.2450 0.4990 0.1788

Peptide transporter 1 (PEPT1), peptide transporter 2 (PEPT2), GABA transporter 2 (GAT2), taurine transporter (TAUT), H+/amino acid transporter 1 (PAT1), ATP-binding cassette transporter G2 (ABCG2), ATP-binding cassette transporter B6 (ABCB6), hydroxymethylbilane synthase (HMBS), uroporphyrinogen III synthase (UROS), uroporphyrinogen III decarboxylase (UROD), coproporphyrinogen oxidase (CPOX), ferrochelatase (FECH), and heme oxigenase 1 (HO-1).