Figure 5.

$\Delta G_{\mathrm{bind}}^{\mathrm{residue}}$ (kcal/mol) of (A) STAT3 and (B) Akt. The amino acids involved in ligand binding are shaded according to their $\Delta G_{\mathrm{bind}}^{\mathrm{residue}}$, in which the highest and lowest energies are ranged from red to magenta, respectively.