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Down-regulation of Cx43 enhances breast cancer metastasis to the lung and liver. (a,c) H&E staining showing metastatic foci in lung and liver tissues, respectively, at week 9 post-injection of parental MDA-MB-231, shCx43 or Cx43D cells. (b,d) qPCR analysis of human 18S ribosomal RNA levels, in lung and liver tissues of mice bearing MDA-MB-231, shCx43 or Cx43D cells.
