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. 2019 Mar 30;11(4):453. doi: 10.3390/cancers11040453

Figure 6.

Figure 6

Withaferin A-mediated autophagy in HCC cells is cytoprotective in nature. (A–D) Cell viability of various HCC cells after treatment with 5 µM WFA alone and in combination with 4 mM of 3MA (3-Methyl adenine), 25 µM CQ or 200 nM bafilomycin, respectively. (E–H) HCC cells were treated with 5 µM WFA alone and in combination with 4 mM 3MA, 25 µM CQ and 200 nM bafilomycin, respectively, and subjected to trypan blue dye exclusion assay. * p < 0.05, compared with Withaferin A; ** p < 0.01, compared with WFA; *** p < 0.001, compared with Withaferin A.