Table 2.
Placebo | PTE100 | PTE300 | |
---|---|---|---|
Glucose (mg/dL) | 161 ± 8.2 | 134 ± 5.8 * | 179 ± 5.5 *# |
Insulin (mU/L) | 42.1 ± 7.8 | 27.7 ± 1.9 | 33.5 ± 2.4 |
NEFA (mEq/L) | 0.556 ± 0.046 | 0.714 ± 0.083 | 0.661 ± 0.113 |
HOMA-IR | 17.0 ± 3.5 | 9.1 ± 0.71 | 14.7 ± 0.94 # |
R-QUICKI | 0.283 ± 0.005 | 0.295 ± 0.005 | 0.281 ± 0.005 |
Data are mean ± SEM; n = 5–6; Parameters were obtained from blood collected at day 22 after a 6 h fast. To compare between two groups, the non-parametric Mann–Whitney U test was used: *, different (p < 0.05) from vehicle; and #, different (p < 0.05) between doses; NEFA—non esterified fatty acids; HOMA-IR—homeostatic model assessment for insulin resistance; R-QUICKI—revised quantitative insulin sensitivity check index; PTE100—100 mg PTE/kg body weight/day; and PTE300—300 mg PTE/kg body weight/day.