Table 3.
Association of age and uremic toxin levels and %PB in children on maintenance HD.
| AgeΔ (n = 170) | Estimate (SE) | p µ |
|---|---|---|
| Small water-soluble uremic toxins | ||
| Uric Acid | 0.00 (0.00) | 0.48 |
| Middle molecules | ||
| β2-microglobulin | 0.00 (0.00) | 0.56 |
| Protein-bound uremic toxins | ||
| p-cresyl glucuronide | ||
| Total levels (mg/dL) | 0.03 (0.01) | 0.03 |
| Protein binding (%) | −0.08 (0.16) | 0.93 |
| Hippuric acid | ||
| Total levels (mg/dL) | 0.03 (0.01) | 0.01 |
| Protein binding (%) | −0.04 (0.22) | 0.99 |
| Indole acetic acid | ||
| Total levels (mg/dL) | −0.001 (0.006) | 0.99 |
| Protein binding (%) | 0.54 (0.19) | 0.01 |
| Indoxyl sulfate | ||
| Total levels (mg/dL) | 0.01 (0.01) | 0.03 |
| Protein binding (%) | 0.21 (0.09) | 0.03 |
| p-cresyl sulfate | ||
| Total levels (mg/dL) | 0.03 (0.01) | <0.01 |
| Protein binding (%) | 0.74 (0.23) | <0.01 |
| CMPF | ||
| Total levels (mg/dL) | 0.04 (0.02) | 0.08 |
Data are (log transformed) estimates with (standard error). p µ: association of uremic toxin concentration and age (years). Δ Analysis corrected for residual kidney function. Significant p-values are marked in bold. SE: standard error.