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Salivary human papillomavirus (HPV)-16 E6/7 viral load in OPC patients. (A) The medium value of the HPV-16 E6/7 viral load showed a trend of being higher in advanced stages (III/IV) when compared to early stages (I/II) of OPC according to the eighth edition staging system. (B) Similarly, based on the eighth edition staging system, salivary HPV-16 viral load (>10 copies/50 ng) was significantly associated with advanced stages OPC.
