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. 2019 Apr 11;11(4):827. doi: 10.3390/nu11040827

Figure 4.

Figure 4

Autophagy at the crossroad between oxidative stress, lipids accumulation and cell death in a hypercaloric diet. Lipid droplets consist of a hydrophobic core of neutral lipids, surrounded by a phospholipid monolayer characterized by perilipins (PLINs) proteins. The core of LDs is composed of triglycerides and cholesterol esters. The figure shows the positive and negative correlation between reactive oxygen species (ROS), autophagy and diet with LDs formation or breakdown.