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Cytotoxicity assay against P388 and HL-60 and L1210 cell lines.
| Compounds | Cell line P388 | Cell line HL-60 | Cell line L1210 |
|---|---|---|---|
| IC50 (μM) a | IC50 (μM) a | IC50 (μM) a | |
| 1 | 36.2 | 21.5 | 22.1 |
| 2 | 20.0 | 12.1 | 8.0 |
| 3 | 61.2 | 41.6 | 27.1 |
| 4 | 9.7 | 6.1 | 8.4 |
| 5 | 15.5 | 6.2 | 10.3 |
| 5-Fluorouracil b | 7.2 | 4.5 | 1.1 |
a DMSO was used as vehicle. b Positive control.
