Table 1.
Predictors of online response: frequency and percentage of online response by patient characteristic and cancer site variables and related crude and adjusted odds ratios of online response (N=63,134).
| Variable | Frequency and percentage of online response | Univariable logistic regression models | Multivariable logistic regression model | ||||
|
|
n (%) | Total, N | ORa (95% CI) | P valueb | aORc (95% CI) | P valueb | |
| Sex |
|
|
|
<.001 |
|
<.001 | |
|
|
Male | 2543 (8.78) | 28,973 | 1 |
|
1 |
|
|
|
Female | 2092 (6.12) | 34,161 | 0.68 (0.64-0.72) |
|
0.50 (0.46-0.54) |
|
| Age group (years) |
|
|
|
<.001 |
|
<.001 | |
|
|
<55 | 1457 (15.28) | 9535 | 2.82 (2.61-3.05) |
|
3.49 (3.21-3.80) |
|
|
|
55-64 | 1377 (10.66) | 12,913 | 1.87 (1.72-2.02) |
|
2.05 (1.89-2.22) |
|
|
|
65-74 | 1347 (6.01) | 22,395 | 1 |
|
1 |
|
|
|
≥75 | 454 (2.48) | 18,291 | 0.40 (0.36-0.44) |
|
0.39 (0.35-0.43) |
|
| IMD score |
|
|
|
<.001 |
|
<.001 | |
|
|
Quintile 1 (least deprived) | 1231 (8.06) | 15,264 | 1 |
|
1 |
|
|
|
Quintile 2 | 1163 (7.84) | 14,832 | 0.97 (0.89-1.05) |
|
0.96 (0.88-1.04) |
|
|
|
Quintile 3 | 1016 (7.33) | 13,853 | 0.90 (0.83-0.98) |
|
0.85 (0.78-0.93) |
|
|
|
Quintile 4 | 749 (6.83) | 10,963 | 0.84 (0.76-0.92) |
|
0.75 (0.68-0.83) |
|
|
|
Quintile 5 (most deprived) | 476 (5.79) | 8222 | 0.70 (0.63-0.78) |
|
0.57 (0.51-0.64) |
|
| Ethnic group |
|
|
|
<.001 |
|
<.001 | |
|
|
White | 4083 (7.03) | 58,067 | 1 |
|
1 |
|
|
|
Nonwhite | 552 (10.89) | 5067 | 1.62 (1.47-1.78) |
|
1.37 (1.24-1.51) |
|
| Cancer sited |
|
|
|
<.001 |
|
.01 | |
|
|
Prostate | 527 (9.21) | 5725 | 1.23 (1.05-1.44) |
|
1.19 (1.01-1.41) |
|
|
|
Leukemia | 220 (9.27) | 2373 | 1.24 (1.02-1.50) |
|
1.15 (0.95-1.41) |
|
|
|
Endometrial | 78 (5.55) | 1406 | 0.71 (0.55-0.93) |
|
1.11 (0.84-1.46) |
|
|
|
Non-Hodgkin lymphoma | 350 (7.88) | 4444 | 1.04 (0.87-1.23) |
|
1.10 (0.92-1.31) |
|
|
|
Colon | 308 (6.80) | 4530 | 0.89 (0.74-1.06) |
|
1.03 (0.86-1.24) |
|
|
|
Other cancers | 1265 (7.76) | 16,292 | 1.02 (0.88-1.18) |
|
1.01 (0.87-1.18) |
|
|
|
Rectal | 235 (7.61) | 3087 | 1 |
|
1 |
|
|
|
Breast | 949 (7.35) | 12,904 | 0.96 (0.83-1.12) |
|
1.00 (0.85-1.18) |
|
|
|
Multiple myeloma | 298 (6.54) | 4555 | 0.85 (0.71-1.02) |
|
0.99 (0.83-1.19) |
|
|
|
Bladder | 239 (5.39) | 4437 | 0.69 (0.57-0.83) |
|
0.96 (0.80-1.17) |
|
|
|
Lung | 166 (4.91) | 3381 | 0.63 (0.51-0.77) |
|
0.83 (0.67-1.02) |
|
|
|
Total | 4635 (7.34) | 63,134 |
|
|
|
|
aUnadjusted odds ratios (ORs) of online response from a series of univariable logistic regression models, conditional on each patient characteristic and cancer site variable considered.
bP values from joint Wald tests.
cAdjusted odds ratios (aORs) of online response from a multivariable logistic regression model, conditional on all patient characteristic and cancer site variables considered.
dResponders with renal and thyroid cancers (grouped into the “other” category) and melanoma skin cancer excluded due to their ethnic group being suppressed or missing.