Table 1.

MHS cell inflammatory cytokines/chemokine response following 4 h treatment with the binary PAH mixture.

PAH Dose * (μM)	Cox2		Tnf		Kc		Mcp1		Il6		Il1β
	Ave	SEM	Ave	SEM	Ave	SEM	Ave	SEM	Ave	SEM	Ave	SEM
0	1.02	0.13	1.01	0.03	1.01	0.11	1.00	0.06	1.04	0.19	1.00	0.07
5	1.70	0.15	1.51	0.11	1.37	0.35	1.22	0.07	1.33	0.38	2.01	0.35
10	1.02	0.09	1.41	0.19	1.28	0.20	1.55	0.42	1.72	0.35	2.79	0.30 **
15	2.30	0.44 **	2.46	0.30 **	1.81	0.32	1.97	0.16	1.73	0.12	5.42	0.16 **
20	2.18	0.11 **	2.78	0.25 **	3.09	1.13 **	2.02	0.31	3.20	0.67 **	6.26	0.16 **

* Binary PAH mixture (1:1 ratio of 1-methylanthracene and fluoranthrene); 0 is DMSO only. ** p < 0.05 compared to 0 (control; DMSO). Cox2, cyclooxygenase 2; Tnf, tumor necrosis factor; Kc, Cxcl1, keratinocyte chemoattractant; Mcp1, Ccl1, monocyte chemoattractant protein 1; and IL6, interleukin 6.