Table 3.
Statistically significant SNPs in oral cavity carcinoma.
| SNPs | Genotype | Oral Cavity | Control | p-Value | OR (CI 95%) | ||
|---|---|---|---|---|---|---|---|
| N | % | N | % | ||||
| IL2 rs2069762 | TT | 43 | 61.4 | 31 | 44.3 | / | 1.00 |
| TG | 22 | 31.4 | 27 | 38.6 | 0.152 | 0.587 (0.284–1.217) | |
| GG | 5 | 7.1 | 12 | 17.1 | 0.039 | 0.300 (0.096–0.940) | |
| Recessive | TT+TG | 65 | 92.9 | 58 | 82.9 | / | 1.00 |
| GG | 5 | 7.1 | 12 | 17.1 | 0.078 | 0.372 (0.124–1.119) | |
| Dominant | TT | 43 | 61.4 | 31 | 44.3 | / | 1.00 |
| TG+GG | 27 | 38.6 | 39 | 55.7 | 0.043 | 0.499 (0.254–0.979) | |
| IL6 rs1800795 | CC | 25 | 35.7 | 39 | 55.7 | / | 1.00 |
| CG | 33 | 47.1 | 23 | 32.9 | 0.031 | 2.238 (1.077–4.653) | |
| GG | 12 | 17.1 | 8 | 11.4 | 0.104 | 2.340 (0.839–6.528) | |
| Recessive | CC+CG | 58 | 82.9 | 62 | 88.6 | / | 1.00 |
| GG | 12 | 17.1 | 8 | 11.4 | 0.337 | 1.603 (0.612–4.203) | |
| Dominant | CC | 25 | 35.7 | 39 | 55.7 | / | 1.00 |
| CG+GG | 45 | 64.3 | 31 | 44.3 | 0.018 | 2.265 (1.148–4.467) | |
| BCL2 rs2279115 | CC | 13 | 18.6 | 27 | 38.6 | / | 1.00 |
| CA | 43 | 61.4 | 30 | 42.9 | 0.008 | 2.977 (1.325–6.688) | |
| AA | 14 | 20.0 | 13 | 18.6 | 0.116 | 2.237 (0.820–6.103) | |
| Recessive | CC+CA | 56 | 80.0 | 57 | 81.4 | / | 1.00 |
| AA | 14 | 20.0 | 13 | 18.6 | 0.830 | 1.096 (0.473–2.540) | |
| Dominant | CC | 13 | 18.6 | 27 | 38.6 | / | 1.00 |
| CA+AA | 57 | 81.4 | 43 | 61.4 | 0.010 | 2.753 (1.273–5.952) | |
Statistically significant results in bold.