Figure 2.

Comparison of COG distributions in AMD samples

Comparisons of the distributions of COGs shared in all species, bacteria, and archaea, respectively. The vertical axis shows the different COG categories and the percentage of shared COGs in each category is shown on the horizontal axis. Asterisks indicate that the enrichments are significant (Fisher’s exact test, P < 0.05). COG refers to Clusters of Orthologous Groups. The COG categories are listed as follows. J, translation, ribosomal structure and biogenesis; K, transcription; L, replication, recombination and repair; V, defense mechanisms; T, signal transduction mechanisms; M, cell wall/membrane/envelope biogenesis; N, cell motility; U, intracellular trafficking, secretion, and vesicular transport; O, posttranslational modification, protein turnover, chaperones; X, mobilome: prophages, transposons; C, energy production and conversion; G, carbohydrate transport and metabolism; E, amino acid transport and metabolism; F, nucleotide transport and metabolism; H, coenzyme transport and metabolism; I, lipid transport and metabolism; P, inorganic ion transport and metabolism; R, general function prediction only; S, function unknown.