Table 3.

Prognostic factors for PFS of CRC patients identified by univariate and multivariate Cox regression analyses.

Variables	Univariate Cox Regression			Multivariate Cox Regression
	Hazard Ratio	95% CI	p-Value	Hazard Ratio	95% CI	p-Value
Age (<65 vs. ≥65 years)	1.490	0.742–2.995	0.263
Sex (male vs. female)	0.799	0.406–1.572	0.517
BMI (<18.5 vs. ≥18.5 kg/m2)	0.382	0.158–0.922	0.032	0.231	0.085-0.631	0.004
BMI (<24 vs. ≥24 kg/m2)	0.976	0.496–1.919	0.943
Stage (I vs. II vs. III vs. IV)	7.631	4.310–13.511	<0.001	7.305	3.996-13.355	<0.001
Location (colon vs. rectum)	1.867	0.954–3.651	0.068
Differentiation (well vs. intermediate vs. poor)	1.721	0.930–3.187	0.084
CEA (<5 vs. ≥5 ng/mL)	4.746	2.319–9.716	<0.001
Albumin (<3.5 vs. ≥3.5 g/dL)	0.454	0.234–0.882	0.020
CRP (<5 vs. ≥5 mg/dL)	4.213	1.837–9.662	0.001
mGPS (0 vs. 1 vs. 2)	1.689	1.179–2.419	0.004
Glutamine (<52 vs. ≥52 ng/μL)	0.234	0.097–0.564	0.001	0.367	0.143–0.941	0.037

Abbreviations: BMI, body mass index; CEA, carcinoembryonic antigen; CRP, C-reactive protein; mGPS, modified Glasgow prognostic score.