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. 2019 Apr 10;11(4):508. doi: 10.3390/cancers11040508

Figure 1.

Figure 1

Consensus kinase sites in HOXB4 and HOXB7. The relative positions of the conserved hexapeptide domain (“HEX”) that mediates Pre-B-cell Leukaemia Homeobox (PBX) binding and the homeodomain (“HD”) that mediates DNA binding are shown. ATM, kinase mutated in ataxia telangiectasia; ATR, ataxia telangiectasia and Rad3-related protein; CK2, casein kinase 2; CDK, cyclin-dependent kinase; CLK, CDC2-like kinase; MAP3K19, mitogen-activated protein kinase kinase kinase 19 (also known as RCK and YSK); PKA, protein kinase A; PKC, protein kinase C; SLK, STE-20 like serine/threonine protein kinase.