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. 2019 Apr 24;11(4):378. doi: 10.3390/v11040378

Figure 8.

Figure 8

Analysis of the PI3K/Akt/NF-κB and MEK1/2 signaling pathways after FUT8 over-expression in Huh7.5.1 cells. Western blot analysis of the expression of PI3K/Akt/NF-κB signaling molecules after HCV infection (A) and FUT8 overexpression (C) in Huh7.5.1 cells. A representative blot from three independent experiments is shown here. The statistical analyses of (A,C) are also listed in (B,D). Different time point expressions of p-MEK1/2 (E) signaling molecules were detected by Western blot. QRT-PCR analysis of the mRNA expression of MRP1 (F) and P-gp (G) by the inhibitors of PI3K (LY294002), p-MEK (PD98095) and NF-κB (Bay11-7082) after HCV infection in Huh7.5.1 cells. * p < 0.05, control group vs. PD98059-treated group; ** p < 0.01, control group vs. Bay11-7082-treated group.