Figure 1.

Protective effects of GBE against alcohol-induced hepatic steatosis. (A) Representative hematoxylin and eosin (H&E) staining of the liver, (B) Liver triglyceride (TG) contents, (C) Representative immunohistochemical staining for hepatic cleaved sterol regulatory element-binding protein 1 (SREBP-1) (red), (D) Western blot of hepatic fatty acid synthase (FAS), acetyl-CoA carboxylase (ACC), phospho-ACC (p-ACC), and cleaved SREBP-1 expression with quantitative data. CON, control; SIL, silymarin; GBE, water extract of G. bimaculatus. Data are shown as means ± SEM (n = 4 for A and C and n = 8 for B and D). * p < 0.05 vs. EtOH control group.