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. 2019 Apr 16;11(4):857. doi: 10.3390/nu11040857

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Protective effects of GBE against alcohol-induced intestinal hyperpermeability and oxidative stress. (A) Representative H&E staining of the small intestine, (B) Western blot of intestinal phospho-myosin light chain kinase (p-MLCK), phospho-Rho-associated protein kinase (p-ROCK), and phospho-Src-family kinase (p-srcFK) with quantitative data, (C) Representative immunohistochemical staining for intestinal 8-OHdG with quantitative data. CON, control; SIL, silymarin; GBE, water extract of G. bimaculatus. Data are shown as means ± SEM (n = 4 for A and C and n = 8 for B). * p < 0.05 vs. EtOH control group.