Figure 1.
Effect of rosmarinic acid and sinapic acid on the AOPP and TBARS content in the lenses of ovariectomized rats. Rosmarinic acid at doses of 10 mg/kg (OVX + RA10) and 50 mg/kg (OVX + RA50), sinapic acid at doses of 5 mg/kg (OVX + SA5) and 25 mg/kg (OVX + SA25) or estradiol at a dose 0.2 mg/kg (OVX + ESTR) were administered orally to ovariectomized rats, once daily for 28 days. SHAM: sham-operated control rats; OVX: ovariectomized control rats; TBARS: thiobarbituric acid reactive substances; AOPP: advanced oxidation protein products. Results are presented as the mean ± SEM. One-way ANOVA followed by Duncan’s test were used for evaluation of the significance of the results. *** p < 0.001: significant differences with regard to the SHAM control rats. ^^ p < 0.01, ^^^ p < 0.001—significant differences with regard to the OVX control rats. No statistically significant differences in results for TBARS were demonstrated by ANOVA.