Figure 3.
Effect of rosmarinic acid and sinapic acid on the amyloid β1-42 content and on the GSH/GSSG ratio in the lenses of ovariectomized rats. Rosmarinic acid at doses of 10 mg/kg (OVX + RA10) and 50 mg/kg (OVX + RA50), sinapic acid at doses of 5 mg/kg (OVX + SA5) and 25 mg/kg (OVX + SA25) or estradiol at a dose 0.2 mg/kg (OVX+ESTR) were administered orally to ovariectomized rats, once daily for 28 days. SHAM: sham-operated control rats; OVX: ovariectomized control rats. Results are presented as the mean ± SEM. One-way ANOVA followed by Duncan’s test were used for evaluation of the significance of the results. ** p < 0.01, *** p < 0.001: significant differences with regard to the SHAM control rats.