Table 1.
Effects of rosmarinic acid and sinapic acid on the average lens mass and lens soluble protein content in ovariectomized rats.
Parameter/Group | SHAM | OVX | OVX + ESTR | OVX + RA10 | OVX + RA50 | OVX + SA5 | OVX + SA25 |
---|---|---|---|---|---|---|---|
Average mass of the lens (g) | 0.059 ± 0.002 | 0.058 ± 0.003 | 0.055 ± 0.002 | 0.055 ± 0.001 | 0.056 ± 0.002 | 0.056 ± 0.002 | 0.055 ± 0.001 |
Soluble protein (mg/g of the lens) |
280.6 ± 6.8 | 302.5 ± 7.8 | 295.8 ± 5.8 | 290.4 ± 3.2 | 291.7 ± 7.2 | 291.9 ± 5.2 | 286.7 ± 4.2 |
Rosmarinic acid at doses of 10 mg/kg (OVX+RA10) and 50 mg/kg (OVX+RA50), sinapic acid at doses of 5 mg/kg (OVX+SA5) and 25 mg/kg (OVX+SA25) or estradiol at a dose 0.2 mg/kg (OVX+ESTR) were administered orally to ovariectomized rats, once daily for 28 days. SHAM: sham-operated control rats; OVX: ovariectomized control rats. Results are presented as the mean ± SEM. No statistically significant differences in results for both parameters were demonstrated by ANOVA.