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. 2019 Mar 28;17(4):197. doi: 10.3390/md17040197

Figure 2.

Figure 2

Ascophyllan activates NK cells in mice. Mice were injected with either ascophyllan (Asco, 50 mg/kg) or fucoidan (Fuco, 50 mg/kg). Six hours after injection, the spleens were harvested, and the splenocytes were incubated in a monensin solution for 4 h. (A) Intracellular IFN-γ levels in spleen NK cells (left panel). Mean percentage of IFN-γ-producing NK cells (right panel). (B) Serum concentration of IFN-γ 6 h after either ascophyllan or fucoidan treatment. (C) CD69 expression levels in spleen NK cells (left panel) 6 h after treatment. Mean fluorescence intensity (MFI) of CD69 levels (right panel). Data represent the mean ± standard error of the mean (SEM) of six samples from three independent experiments, ** p < 0.01.