UV-B-induced inflammatory response. Nitric oxide (NO), inducible NO synthase (iNOS), prostaglandin E2 (PGE2), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and other cytokines, such as interleukin-1 (IL-1) and interleukin-6 (IL-6), are shown as mediators.