Table 1.
IC50 values against 2,2-diphenyl-1-picryhydrazyl (DPPH), 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS), and oxygen radical absorption capacity (ORAC) of mono-, di-substituted MAAs, and glycosylated MAAs.
| Mycosporine-like Amino Acids (MAAs) | IC50 | References |
|---|---|---|
| Mono-Substituted MAAs | ||
| Mycosporine-glycine | 3 µM a at pH 8.5 | [14,52] |
| 43 µM b | [54] | |
| Mycosporine-γ-aminobutyric acid | 0.6 mM a | [14] |
| Di-Substituted MAAs | ||
| Mycosporine-2-glycine | 45 µM a | [54] |
| 22 µM b | [71] | |
| Palythine | 21.3 µM b | [67] |
| 714 µM c | [67] | |
| Porphyra-334 | 133 µM a | [60] |
| 185.2 µM b | [70] | |
| Shinorine | 94 µM a | [60] |
| 399 µM b | [70] | |
| Glycosylated MAAs | ||
| Hexose-bound-P334 | 58 mM a | [69] |
| 7-O-(β-arabinopyranosyl)-P334 | 9.5 mM a | [69] |
| 13-O-β-galactosyl-porphyra-334 | 17 mM a | [69] |
| Standard antioxidants | ||
| Trolox | 10 µM b | [60] |
| Ascorbic acid | 21.3 µM b | [67] |
| α-Tocopherol | 11.1 µM b | [67] |
a Radical scavenging activity measured using ABTS as he organic radical source. b Radical scavenging activity measured using DPPH as the organic radical source. c Radical scavenging activity measured using the ORAC antioxidant assay kit.