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. 2019 May 15;17:83. doi: 10.1186/s12957-019-1618-4

Table 4.

Univariate and multivariate analysis for disease free survival

Covariates Univariate analysis Multivariate analysis
HR 95% CI p value HR 95% CI p value
Age 1.026 (0.995–1.059) 0.096
Female Ref
Male 1.4503 (0.8437–2.493) 0.179
Colon primary Ref
Rectal primary 0.7183 (0.2847–1.812) 0.484
Classic adenocarcinoma Ref
Mucinous adenocarcinoma 1.1205 (0.5979–2.1) 0.723
Grade I (histology) Ref
Grade II (histology) 0.90843 (0.4726–1.746) 0.773
Grade III (histology) 0.73676 (0.3409–1.592) 0.437
Presenting stage I–III Ref
Presenting stage IV 1.4028 (0.8112–2.426) 0.226
Metachronous Ref
Synchronous 1.2770 (0.7426–2.196) 0.377
Peri-op chemo 0.419 (0.1873–0.938) 0.034 0.448 (0.1968–1.022) 0.056
Intra-op IV chemo 1.7762 (0.9555–3.302) 0.069
PCI (continuous) 1.101 (1.059–1.145) 1.09e−06 1.100 (1.047–1.156) 0.0001
Operative time (hours) 1.199 (1.068–1.346) 0.002 1.014 (0.875–1.175) 0.856
Blood loss (100 ml) 1.0177 (0.9875–1.047) 0.265
No complications Ref
Grade I (complication) 1.072 (0.510–1.996) 0.838
Grade II (complication) 1.105 (0.472–2.576) 0.817
Grade III (complication) 1.936 (0.739–5.208) 0.185
Grade IV (complication) 1.849 (0.616–1.795) 0.260

Boldface font indicate statistically significant p values of less than 0.05