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. 2019 May 15;7:75. doi: 10.1186/s40168-019-0689-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Illustration of bile acid pathways in human gut microbes reconstructed for AGORA. a Deconjugation of Tauro-CA/Glyco-CA and subsequent conversion to 12-dehydro-CA, UCA, and Iso-CA. b Deconjugation of Tauro-CDCA/Glyco-CDCA and subsequent conversion to UDCA. c Conversion of CA to DCA via the bai pathway. d Conversion of CDCA to LCA via the bai pathway. e Conversion of UDCA to LCA via the bai pathway. CoA Coenzyme A. For metabolite abbreviations, see Table 1.