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. 2019 May 16;20:381. doi: 10.1186/s12864-019-5737-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Experimental strategy for quantitative proteome analysis and quality control (QC) validation of MS data. a Protein were extracted and trypsin digested in three biological replicates for each sample group. All protein samples were analyzed by HPLC-MS/MS.126–131 label: TMT-126-131 Label Reagent (ThermoFisher Scientific, Shanghai, China). b Length distribution of all identified peptides. c Mass delta of all identified peptides