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The higher enrichment levels of CD8+ T cells were associated with better disease-free survival in the low-stroma-content colon cancers, but not in the high-stroma-content colon cancers. ESTIMATE [19] was used to quantify the intratumoral stromal content (stroma score) of TCGA colon cancer samples. High-stroma-content: stroma score > median; low-stroma-content: stroma score < median.
