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The inflammatory-mediated HTN process, immune cells via different signaling pathways. The known routes, like signal transducer and activator of transcription -1, -3, and -5 (STAT), janus-associated kinases (JAK), domain containing phosphatase (SHP2) or extracellular signal related kinase and phosphatidylinositol-3-kinase (PIK3/AKT), depend on the specific interleukin production.
