FIGURE 4.

Effect of chronic ethanol administration on the nuclear and cytosolic levels of TFEB in rats subjected chronic ethanol feeding and withdrawal. (A) Western blots of nuclear and cytosolic TFEB in livers of rats fed control diet ethanol diet and rats fed ethanol diet and then withdrawn from ethanol and fed control diet for 7 days. (B)–mean levels of nuclear TFEB, (C) mean levels of cytosolic TFEB, and (D) mean hepatic proteasome activities in the three groups of animals, as indicated (figure reproduced from Figure 4 by Thomes et al., 2019 with permission).