Table 2.

Haploid Strains Sensitive to Radicicol and Geldanamycin with Associated Function and Human Homologs.

ORF Systematic	Deletion Strain	Function	Human Homolog
YGR285C	zuo1	J-protein that associates with Hsp70; together, they participate in ribosome biogenesis and protein folding	HSP40
YPLI06C	sse1	Cytosolic HspII0 that is involved in protein folding	HSPII0
YBL008W	hir1	Corepressor protein involved in the transcriptional regulation of histone proteins	HIRA
YNL098C	ras2	Ras GTP-binding protein involved in sporulation, nitrogen starvation, and filament growth	RRAS2
YML07IC	cog8	Golgi complex protein member involved in protein trafficking	COG8
YMR095C	sno1	Can function as a glutaminase; involved in pyridoxine metabolism	N/A
YJR073C	opi3	Phospholipid methyltransferase involved in phosphatidylcholine biosynthesis	PEMT
YGL005C	cog7	Golgi complex protein member involved in protein trafficking	COG7
YIR0I9C	muc1	Cell surface glycoprotein involved in hyphae and biofilm formation	MUCI
YNLI97C	whi3	RNA binding protein involved in cell cycle	N/A
YNL322C	kre1	Cell wall protein	N/A
YKL037W	aim26	Unknown function; altered inheritance rate of mitochondria	N/A
YJLI79W	pfd1	Prefoldin protein that transfers proteins to chaperones; involved in actin and tubulin synthesis	PFDNI