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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Pancreas. 2019 Mar;48(3):323–328. doi: 10.1097/MPA.0000000000001248

TABLE 3.

Univariate Cox Regression Analysis of Overall Survival

Characteristics No. Patients Overall Survival
HR (95% CI) P
Sex
 Female (reference) 34 1.00
 Male 50 1.35 (0.78–2.34) 0.28
Age 84 1.02 (0.99–1.06) 0.15
Tumor differentiation
 Well-moderate (reference) 58 1.00
 Poor 26 1.16 (0.64–2.12) 0.63
pT stage (AJCC 8th edition) 0.09
 pT1 (reference) 12 1.00
 pT2 61 2.89 (1.13–7.42) 0.03
 pT3 11 2.46 (0.77–7.86) 0.13
pN stage (AJCC 8th edition) 0.02
 pN0 (reference) 16 1.00
 pN1 32 2.47 (0.93–6.55) 0.07
 pN2 36 3.85 (1.45–10.19) 0.007
Margin
 Negative (reference) 75 1.00
 Positive 9 5.29 (2.26–12.4) <0.001
PERK expression
 Low (reference) 42 1.00
 High 42 1.77 (1.00–3.12) 0.05
p-eIF2α Expression
 Low (reference) 37 1.00
 High 47 1.94 (1.08–3.50) 0.03