Table 1.
Cohorts Participating in the Liver Cancer Pooling Project.
| Cohort (Reference) | Location | Recruitment/Follow-up | Cohort Characteristics | Baseline Sample Size | Baseline BMI (kg/m2), Mean (SD) | Baseline BMI ≥30 kg/m2, % | Baseline Diabetes, % |
|---|---|---|---|---|---|---|---|
| Total Cohort | |||||||
| ICC | |||||||
| NIH-AARP Diet and Health Study (53) | multiple states | 1995/2008 | AARP members | 564,518 | 27.1 (4.7) | 21.3 | 9.3 |
| 235 | 27.6 (4.8) | 27.2 | 14.0 | ||||
| Agricultural Health Study (54) | North Carolina, Iowa | 1999/2008 | Farmers and spouses | 89,245 | 27.0 (4.6) | 16.4 | 3.2 |
| 6 | 28.6 (2.5) | 16.7 | 33.3 | ||||
| United States Radiologic Technologists Study (55) | multiple states | 1994/2008 | U.S. radiologic technologists | 72,382 | 25.7 (4.9) | 16.0 | 3.2 |
| 1 | – | – | – | ||||
| The Breast Cancer Demonstration Project (56) | multiple states | 1987/1999 | Breast cancer screening program | 51,523 | 25.1 (4.5) | 11.7 | 4.8 |
| 6 | 23.7 (2.5) | 0.0 | 0.0 | ||||
| Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (57) | multiple states | 1993/2009 | Trial of cancer screening modalities | 149,677 | 27.3 (4.8) | 23.6 | 7.7 |
| 42 | 27.0 (3.4) | 14.3 | 4.8 | ||||
| Women’s Health Study (58) | multiple states | 1993/2010 | Trial of low-dose aspirin and vitamin E in prevention of CVD | 39,769 | 26.0 (5.0) | 18.2 | 2.3 |
| 5 | 26.9 (6.0) | 40.0 | 0.0 | ||||
| Health Professionals Follow-Up Study (59) | multiple states | 1986/2010 | Male health professionals, aged 40–75 | 51,358 | 25.5 (3.2) | 8.0 | 3.6 |
| 14 | 25.3 (2.4) | 14.3 | 7.1 | ||||
| NYU Women’s Health Study (60) | New York | 1985/2010 | Study of hormones and breast cancer | 14,225 | 24.9 (4.5) | 12.5 | 1.7 |
| 3 | 25.6 (1.9) | 0.0 | 0.0 | ||||
| Cancer Prevention Study II (61) | U.S., nationwide | 1992/2007 | General population | 160,367 | 26.0 (4.3) | 14.9 | 7.5 |
| 31 | 27.4 (4.2) | 25.8 | 12.9 | ||||
| Iowa Women’s Health Study (62) | Iowa | 1986/2007 | Postmenopausal women, ages 55–69 years | 28,493 | 26.9 (4.9) | 22.5 | 6.2 |
| 10 | 27.6 (5.0) | 30.0 | 10.0 | ||||
| Black Women’s Health Study (63) | multiple states | 1995/2009 | General population, self-identified as black or African American | 56,771 | 27.7 (6.2) | 28.7 | 3.3 |
| 1 | – | – | – | ||||
| Women’s Health Initiative (64) | multiple states | 1993/variable | Postmenopausal women, ages 50–79 years | 160,677 | 27.8 (5.6) | 29.3 | 5.0 |
| 46 | 29.9 (6.5) | 34.8 | 13.0 | ||||
| Nurses’ Health Study (65) | multiple states | 1980/2010 | Married, female nurses, aged 30–55 | 102,138 | 24.4 (4.5) | 10.8 | 2.4 |
| 14 | 25.9 (4.0) | 21.4 | 7.1 | ||||
| TOTAL | 1,541,143 | 26.7 (4.9) | 19.8 | 6.5 | |||
| 414 | 27.6 (4.8) | 25.4 | 12.1 | ||||