Figure 1.

Concurrent decline of cognition and mobility in aging and neurodegeneration. Gray Arrows: cognitive impairment predicts dementia with Mild Cognitive Impairment (MCI) as an intermediate state. Gait impairments increase fall risk and slow gait mediates the association. White Arrows show that cognitive and gait impairments, as well as dementia and falls, are interrelated (arrow thickness represents the strength of associations). Dashed Arrows represent that gait abnormalities (slow gait, high dual-task cost) can predict dementia; similarly, executive and memory dysfunction can predict fall risk. Note: DTC = Dual-task gait cost. Adapted from Montero-Odasso et al. (1) and Amboni et al. (6).