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. 2018 Sep 15;74(6):794–801. doi: 10.1093/gerona/gly209

Figure 3.

Figure 3.

Effects of age and HIV infection on MINCLE protein expression in monocyte subsets. HIV-negative young adults (n = 20), HIV-negative older adults (n = 18), HIV-positive young adults (n = 10), HIV-positive older adults (n = 10) were assessed. Shown are dot plots depicting MINCLE protein expression (Mean Fluorescence Intensity (MFI)) as assessed by flow cytometry for (a) Inflammatory (CD14+CD16+) (b) Classical (CD14+CD16lo) (c) Activated (CD11b+CD14+), and (d) Nonclassical (CD14+CD16hi) monocytes. Statistically significant comparisons, indicated by asterisks, were noted using a Wilcoxon two-sample test with t approximation, with an additional false discovery rate adjustment: Classical monocytes, HIV-negative older versus young adults, (p = .003); HIV-positive versus HIV-negative young adults, (p = .005); non-classical monocytes, HIV-negative older versus young adults, (p = .003), and HIV-positive versus HIV-negative young adults, (p = .03). All other comparisons did not reach statistical significance as observed in this study.