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. 2019 Apr 12;54(6):1955–1968. doi: 10.3892/ijo.2019.4782

Figure 3.

Figure 3

Effects of overexpressing or silencing MTDH on cell invasion and migration in prostate normal and cancer cell lines. (A) Cell scratch wound assay was carried out to detect the effects of the overexpression or silencing of MTDH on the migration of the normal PWR-1E cells or 3 prostate cancer (PCa) cell lines (PC-3, LNCaP and DU145 cells). (B) Transwell assay was performed to detect the effects of the overexpression or silencing of MTDH on invasion of PWR-1E normal cells or 3 PCa cell lines (PC-3, LNCaP and DU145 cells). (C) Relative invasion rates are shown as bar diagrams. (D) Relative migration rates are shown as bar diagrams. Data are shown as the means ± SD from 3 independent experiments [**P<0.01, compared with control; ^^P<0.01, compared with mock/negative control (NC) groups]. MTDH, metadherin.