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. 2019 Apr 12;54(6):1955–1968. doi: 10.3892/ijo.2019.4782

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Copyright: © Pan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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MTDH reverses the suppressive effects of miR-145-5p and miR-145-3p mimics on PCa cell invasion. (A) Cell invasion was examined by Transwell assay in PC-3 and LNCaP cells. (B) The effects of MTDH overexpression on the decreased invasion of PC-3 and LNCaP cells induced by miR-145-5p/miR-145-3p mimics are shown as bar diagrams. Data are shown as the means ± SD from 3 independent experiments [^{^^}P<0.01, compared with mock/negative control (NC); ^##P<0.01, compared with miR-145-5p mimic; ^&&P<0.01, compared with miR-145-3p mimic]. MTDH, metadherin.