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Effects of exposure of LoVo WT and LoVo DX cells to ZmPAO and spermine on the morphology observed by scanning electron microscopy (SEM). (A-C) LoVo WT and (D-F) LoVo DX cells were incubated at 37°C for 60 min; (A and D) untreated cells; (B and E) cells treated with 18 µM H2O2 alone; (C and F) cells treated with ZmPAO and 18 µM spermine. Scale bars, 20 µm. ZmPAO, maize polyamine oxidase; LoVo WT cells, LoVo wild-type cells; LoVo DX cells, LoVo multidrug-resistant cells.
