Table II.
Characteristics | No. of patients |
---|---|
Age (years) | |
Mean, 62.3±13.8 | |
Range, 27-93 | |
Primary tumora | |
T1 | 30 |
T2-T4 | 81 |
Stage groupinga | |
II | 88 |
III | 23 |
Molecular subtypes | |
Luminal A likeb | 42 |
Luminal B like | 34 |
Luminal-HER2 | 7 |
HER2 | 12 |
TNBC | 16 |
ER | |
Positive | 83 |
Negative | 28 |
PgR | |
Positive | 72 |
Negative | 39 |
HER2 | |
Positive | 20 |
Negative | 91 |
Ki67 | |
<30% | 68 |
≤30% | 43 |
Nuclear gradea | |
1 | 24 |
2 | 45 |
3 | 42 |
Histological classificationc | |
Invasive ductal carcinoma (total) | 82 |
Special (total) | 29 |
Mucinous carcinoma | 4 |
Medullary carcinoma | 1 |
Invasive lobular carcinoma | 16 |
Apocrine carcinoma | 2 |
Spindle cell carcinoma | 2 |
Invasive micropapillary carcinoma | 1 |
Carcinoma with neuroendocrine features | 3 |
The grade of the tumor and stages were defined according to the UICC (TNM) classification.
Luminal A like were defined as ER+, PgR >20%, HER2− and Ki67 <30%.
The classification were defined according to the Japanese Breast Cancer Society (17th edition) (17). ER, estrogen receptor; PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2.