Expression of HOXA6 in carcinoma tissues and transfected cell lines, and survival analysis. (A) The mRNA expression levels of HOXA6 in ten paired ccRCC tumor and normal tissues extracted from GSE6344. ***P<0.001 vs. Normal. (B) Survival analysis of patients with ccRCC, which was performed using Gene Expression Profiling Interactive Analysis. (C) The expression of HOXA6 protein in ccRCC and normal tissues as detected by immunohistochemistry. ***P<0.001 vs. Normal. (D) Expression of HOXA6 in transfected cell lines. **P<0.01 vs. vector or NC. ***P<0.001 vs. vector. ccRCC, clear cell renal cell carcinoma; HOXA6, homeobox A6; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; vector, vector-only control; NC, negative control; shHOXA6, HOXA6 short hairpin RNA; ACTB, β-actin; TPM, transcripts per kilobase of exon model per million mapped reads.