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. Author manuscript; available in PMC: 2019 May 16.
Published in final edited form as: Vaccine. 2018 Jul 25;36(35):5325–5332. doi: 10.1016/j.vaccine.2018.06.054

Figure 2. Clonal Lineage Repertoires Show Robust Clonal Expansion.

Figure 2

Paired heavy and light chain sequences isolated from subject-drawn PBMCs were analyzed In slllco and grouped into related lineages—where a lineage is defined as a family of clones with identical HCDR3 regions. Lineages isolated in circulation at multiple time points are highlighted a specific color. Lineages present at only a single time point are shown in grayscale. Clonal lineages 6515[16] and 6649[15] are emphasized where present.