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. Author manuscript; available in PMC: 2019 May 16.
Published in final edited form as: Expert Rev Vaccines. 2017 Dec 27;17(2):107–114. doi: 10.1080/14760584.2018.1419068

Figure 2.

Figure 2.

CMB305 schedule. LV305 (blue arrows) is used as the priming agent given for 4 doses, starting day 1 then days 21, 49 and 77. The boosting regimen is called ‘G305’ (red arrows) and starts on day 35 every 4 weeks for three doses and then every 8 weeks for up to 1 year. The G305 regimen includes whole recombinantly expressed NY-ESO-1 protein and the synthetic toll like receptor 4 (TLR4) agonist GLA (Glucopyranosyl lipid A) formulate in a stable oil-in-water emulsion (GLA-SE). Full color available online.