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. 2019 May 16;14(5):e0215946. doi: 10.1371/journal.pone.0215946

Fig 2. MHC heterozygosity drives functional divergence among individuals.

Fig 2

A) PCoA of functional beta-diversity comparison between MHC homozygote and MHC heterozygote animals based on Bray-Curtis analysis of PICRUSt-annotated KEGG Orthology (KO) genes (ANOSIM: R = 0.03; P = 0.23; no. of permutations = 99). B) The number of functional genes is compared between MHC homozygote and MHC heterozygote animals. C) Boxplots representing within-group functional dissimilarity comparisons between MHC homozygotes and MHC heterozygotes based on Bray-Curtis analysis. D) Boxplots representing within-group predicted KO gene dissimilarity between MHC homozygote and MHC heterozygote animals based on Bray-Curtis analysis. Symbol (****) indicates Benjamini-Hochberg corrected significance values of P < 0.0001, which were calculated using non-parametric two sample t-test.