Table 1.
Measured HPLC peak area for different PK11195 concentrations, repeatability and reproducibility of the developed analytical method. All data shown as average response±SD (n = 6), D1 = the 1st day of sample analysis and D2 = the 2nd day of sample analysis.
| Concentration of PK11195 |
||||
|---|---|---|---|---|
| 7.5 ng/mL | 10 ng/mL | 15 ng/mL | 25 ng/mL | |
| Average response D1 (mAU·min) | 0.010 ± 0.002 | 0.011 ± 0.001 | 0.012 ± 0.002 | 0.020 ± 0.003 |
| Repeatability D1 (%) | 22 | 11 | 7 | 5 |
| Average response D2 (mAU·min) | 0.009 ± 0.001 | 0.010 ± 0.001 | 0.013 ± 0.001 | 0.023 ± 0.001 |
| Repeatability D2 (%) | 14 | 13 | 5 | 6 |
| Intermediate precision D1 vs. D2 (%) | 24 | 13 | 15 | 17 |