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CNS myelination is delayed and decreased in R167Q+/+ mice. (A) Representative western blot assessing MBP levels in cerebrums of R167Q+/+ males and sex-matched wild-type littermates at postnatal days (P)13, 14 and 15. (B) Micro-MRI evaluation of brain myelin volumes. Shown are the means ± SDs (n = 3) of brain myelin volumes normalized by brain volumes in 3-month-old R167Q+/+ males and wild-type (WT) male littermates. *P < 0.01, Student t-test.
