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Heme content in the R167Q+/+ mice is similar to that of the T1/T2 mice. (A) Total heme content in liver and brain tissues from wild-type (WT), R167Q+/+ and T1/T2 male mice and (B) heme saturation of tryptophan dioxygenase in wild-type and R167Q+/+ livers are presented as means ± SDs (n ≥ 3).
