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Tissue and erythrocyte HMBS activities in R167Q+/+ and wild-type mice
| Tissue | HMBS activity (nmol/hr/mg protein) | ||
|---|---|---|---|
| Wild type | R167Q+/+ | Wild type, % | |
| Liver | 273 ± 47 | 13.5 ± 2.4 | 4.9 |
| Kidney | 216 ± 23 | 17.1 ± 9.8 | 7.9 |
| Heart | 222 ± 14 | 11.8 ± 2.5 | 5.3 |
| Brain | 90 ± 19 | 4.3 ± 0.4 | 4.8 |
| Erythrocytes | 509 ± 93 | 29.5 ± 2.8 | 5.8 |
HMBS activities are presented as means ± SDs (n = 3–5) and percentages of wild-type activity.
